Applikon Bioreactor introduces the micro-Matrix, a revolutionary system offering precise control over 24 independent bioreactors within the compact footprint of a microtiter plate. Each of the 24 bioreactors provides autonomous management akin to larger stirred-tank counterparts:

- pH regulation with measurement and dual-sided control 

- Temperature management with measurement and dual-sided control, including plate-wide gradients 

- Dissolved oxygen control with measurement and dual-sided regulation 

- Customizable liquid additions, including feeding profiles 

- Up to 4 distinct gas additions, each independently controlled

The micro-Matrix faithfully replicates the functionality of small-scale bioreactors. Its bioreactor square well cassette design, modeled after the widely adopted SBS-format microtiter plates, ensures optimal mixing, gas transfer, and seamless integration into laboratory automation workflows. The user-friendly PC-based interface mirrors the renowned my-Control interface, facilitating intuitive interaction with all 24 bioreactors. 

Integrated LEDs provide instant process feedback, indicating bioreactor status (inactive/active/alarm) through color-coded signals, streamlining operator oversight. Each bioreactor boasts its own PID controller for pH, dissolved oxygen, and temperature, allowing for precise adjustments. pH control methods include gas addition, liquid addition, or a combination of both, while dissolved oxygen levels can be finely tuned via up to four gas additions per bioreactor.

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Question & Answers For:

Applikon Bioreactor

Past Questions, Helpful Answers.

q.

What applications is the Applikon Bioreactor suitable for?

a.

The Applikon Bioreactor is designed for a wide range of applications, including microbial fermentation, cell culture, and bioprocess development in research and industrial settings.

q.

What types of cultures can I grow in the Applikon Bioreactor?

a.

You can grow both microbial and mammalian cell cultures, including bacteria, yeast, and mammalian cells, making it versatile for various research needs.

 

q.

How easy is it to operate the Applikon Bioreactor?

a.

The Applikon Bioreactor features an intuitive user interface and automated controls, making it user-friendly for both experienced researchers and beginners.

q.

What is the capacity of the Applikon Bioreactor?

a.

The capacity can vary depending on the specific model, but it typically ranges from small-scale (1-5 liters) to larger setups (up to 100 liters or more), accommodating different research scales.

q.

Can I monitor the parameters in real-time?

a.

Yes, the Applikon Bioreactor allows for real-time monitoring of critical parameters such as pH, temperature, dissolved oxygen, and agitation speed, ensuring optimal culture conditions.

q.

Is the system compatible with various sensor types?

a.

The Applikon Bioreactor is compatible with a variety of sensors, allowing you to customize the setup according to your specific research needs.

q.

What materials are used in the construction of the bioreactor?

a.

The bioreactor is typically made from high-quality materials such as glass or stainless steel, ensuring durability and resistance to corrosion and contamination.

q.

Does the bioreactor support scale-up processes?

a.

Yes, the Applikon Bioreactor is designed to facilitate scale-up processes, enabling researchers to transition from small-scale experiments to larger production runs efficiently.

q.

Are there any software features included?

a.

The Applikon Bioreactor often comes with integrated software for data logging, process control, and analysis, enhancing the research experience and providing valuable insights.

q.

Can I integrate the bioreactor with other laboratory equipment?

a.

Yes, the Applikon Bioreactor can be integrated with various laboratory systems, such as chromatography or filtration setups, allowing for a seamless workflow in your research processes.